FIG 5.

Cytotoxicity of DABCO derivatives on mammalian oral cells. PDL cells, GF, or primary EPI cells were exposed to BisGMA (positive-control compound) or DABCO compounds dissolved in RPMI medium at concentrations ranging from 0 to 32.0 μg/ml. Cytotoxicity was evaluated at 24 h. The data are representative of the results of 2 repeat experiments with 8 replicates/concentration. The yellow filled symbols indicate the lowest drug concentrations with significantly reduced cell survival compared to no drug (P < 0.05 using the unpaired Student t test).