TABLE 1.

In vitro efficacies of the compounds used in this study^a

Cell type	Mean IC50 ± SD
	BKI-1294	BKI-1517	BKI-1553
N. caninum tachyzoites	0.17 ± 0.04	0.05 ± 0.03	0.18 ± 0.03
HFFs	>20	>20	>20
Vero cells	>20	>20	>20
RH cells	>20	>20	>20

^aBased on data from the inhibition assays shown in Fig. 2, IC₅₀s (inhibitory concentrations of 50% of the solvent control value) were calculated as described previously (20) and are given in micromolar concentrations (with 95% confidence intervals).