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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Pediatr Blood Cancer. 2016 Oct 26;64(5):10.1002/pbc.26303. doi: 10.1002/pbc.26303

TABLE 1.

Modified Buchanan and Adix bleeding score, overall bleeding severity

Grade
0 None No new hemorrhage of any kind
1 Minor Few petechiae (≤100 total) and/or ≤ 5 small bruises (≤ 3 cm
diameter), no mucosal bleeding
2 Mild Many petechiae (>100 total) and/or > 5 large bruises (>3 cm
diameter)
3 Low Risk*
Moderate
Blood crusting in nares, painless oral purpura, oral/palatal
petechiae, buccal purpura along molars only, mild epistaxis ≤
5 minutes
High Risk*
Moderate
Epistaxis > 5 minutes, hematuria, hematochezia, painful oral
purpura, significant menorrhagia
4 Severe Mucosal bleeding or suspected internal hemorrhage (brain, lung,
muscle, joint, etc) that requires immediate medical attention or
intervention
5 Life
threatening/
Fatal
Documented intracranial hemorrhage or life threatening or fatal
hemorrhage at any site
*

Modification: Original Buchanan and Adix Grade 3/Moderate- overt mucosal bleeding (epistaxis, gum bleeding, oropharyngeal blood blisters, menorrhagia, gastrointestinal bleeding, etc) that does not require immediate medical attention or intervention