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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Free Radic Biol Med. 2016 Sep 25;105:16–27. doi: 10.1016/j.freeradbiomed.2016.09.024

Fig. 1.

Fig. 1

H. pylori-infected macrophages produces H2O2 from L-arginine. H. pylori induces SLC7A2 expression allowing the uptake of L-arginine in macrophages. The induction of ARG2, ODC, which requires a MYC-dependent pathway, and SMOX leads to the release of H2O2.