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. 2017 Mar 24;17:228. doi: 10.1186/s12879-017-2316-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Anti-Vacc-C5-specific antibodies (AB) in serum. a AB levels for the total cohort at week 1 (baseline), 6 (after initial immunisation), 15 (after1^st boost) and 26 (after 2nd boost, end of study). Data are given as medians, interquartile and overall ranges. The change from baseline to end of study is indicated (Wilcoxon matched pairs test). b AB levels for the three dose groups at week 1, 6, 15 and 26. LD = low, MD = median and HD = high dose. Data are given as medians, interquartile and overall ranges. Changes within each dose group with p-values less than 0.10 are indicated (Wilcoxon matched pairs test)