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. 2017 Mar 24;17:228. doi: 10.1186/s12879-017-2316-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Vacc-C5-specific IFN-γ responses. a IFN-γ responses for the total cohort at week 1 (baseline), 6 (after initial immunisation), 15 (after1^st boost) and 26 (after 2nd boost, end of study). Data are given as medians, interquartile and overall ranges. Changes with p-values less than 0.10 are indicated (Wilcoxon matched pairs test). b IFN-γ responses for the three dose groups at week 1, 6, 15 and 26. LD = low, MD = median and HD = high dose. Data are given as medians, interquartile and overall ranges. Significant changes within each dose group are indicated (Wilcoxon matched pairs test)