Table 2.
Cardiac morphometry parameters in control and MCT-treated (at 2, 4, and 6 weeks) rats
Group | CON-2 W (n = 8) |
MCT-2 W (n = 12) |
CON-4 W (n = 8) |
MCT-4 W (n = 10) |
CON-6 W (n = 8) |
MCT-6 W (n = 8) |
---|---|---|---|---|---|---|
RV/LV + IVS (g/g) | 0.24 ± 0.02 | 0.27 ± 0.02* | 0.25 ± 0.02 | 0.48 ± 0.06**※※ | 0.23 ± 0.03 | 0.62 ± 0.09 **※※△ |
RV/BW (g/kg) | 0.48 ± 0.02 | 0.53 ± 0.02* | 0.49 ± 0.04 | 0.85 ± 0.06**※※ | 0.45 ± 0.03 | 1.22 ± 0.07**※※△ |
BW Body weight, LW Lung weight, RV Right ventricle, LV Left ventricle, IVS Interventricular septum, MCD Myocardium cell diameter
Data are presented as mean ± standard deviation. * P < 0.05 and ** P < 0.01, versus age-matched rat; ※ P < 0.05, ※※ P < 0.01, versus MCT-2 W; △ P < 0.05, versus MCT-4 W