Table 5.

KEGG pathways identified for the upregulated genes in the high-RFI group with an FDR q-value < 0.01 from the output of the GSEA in the Jerseys

	Pathways name	FDR q-value	Core enrichment gene
1	Retinol metabolism	0.002	PNPLA4, CYP2B6, CYP2C18, RETSAT, CYP1A1, RDH11, CYP1A2, ALDH1A1, CYP26B1, LRAT, ADH5, UGT2A3, RDH16, UGT1A1, ALDH1A2, RDH10
2	Metabolism of xenobiotics by cytochrome P450	0.003	CYP2B6, ALDH1A3, CYP2E1, CYP2C18, EPHX1, CYP1A1, CYP1A2, MGST1, MGST3, ALDH3B1, ADH5, UGT2A3, UGT1A1
3	Ether lipid metabolism	0.009	ENPP6, PLA2G7, PLD2ENPP2, LPCAT2PLA2G12A, AGPSPLD1

FDR q-value = adjusted p-value; core enrichment gene = subset of genes that contributes most to the enrichment result