Table 6.
Treatments | CAT (mmol H2O2/mg protein) | SOD (units/mg protein) | TBARS (mmol/mg protein) |
---|---|---|---|
H2O + Scop | 58.6 ± 4.6c | 0.8 ± 0.2c | 1.3 ± 0.2b |
39.3 + Scop | 115.8 ± 1.1∗ | 2.4 ± 0.12∗ | 0.8 ± 0.1∗ |
98.25 + Scop | 251.4 ± 32.6∗∗∗ | 5.1 ± 0.5∗∗ | 0.6 ± 0.1∗∗ |
196.5 + Scop | 274.4 ± 8.8∗∗∗ | 4.9 ± 0.2∗∗ | 0.6 ± 0.1∗∗ |
393 + Scop | 325.0 ± 18.9∗∗∗ | 6.4 ± 0.4∗∗∗ | 0.6 ± 0.1∗∗ |
Pira + Scop | 179.2 ± 9.0∗∗ | 4.7 ± 0.3∗∗ | 0.7 ± 0.1∗∗ |
H2O + H2O | 244.5 ± 10.9∗∗∗ | 6.7 ± 0.2∗∗∗ | 0.6 ± 0.1∗∗ |
Data are mean ± SEM, n = 5 per dose. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 as compared with scopolamine-treated group (H2O + Scop), one-way ANOVA followed by Duncan's test; bP < 0.01, cP < 0.001 compared to the normal control group (H2O + H2O), one-way ANOVA followed by Duncan's test. Pira: piracetam, H2O: distilled water, CAT: catalase, SOD: superoxide dismutase, TBARS: thiobarbituric acid reactive substance activity.