Table 2.
The distribution of genotypes and allele frequencies and the analysis of the odds ratio (OR) for 51Gln/His polymorphism of APEX gene in patients with colorectal cancer (CRC) and the control group.
| Genotype/allele | Patients (n = 311) | Controls (n = 302∗) | OR (95% CI) | p |
|---|---|---|---|---|
| Gln/Gln | 69 | 92 | 1 (ref) | — |
| Gln/His | 206 | 161 | 1.706 (1.174–2.480) | 0.005 |
| His/His | 36 | 49 | 0.979 (0.576–1.667) | 0.920 |
| Gln | 344 | 345 | 1 (ref) | — |
| His | 278 | 259 | 1.077 (0.859–1.349) | 0.522 |
∗Genotype distribution in the Hardy-Weinberg equilibrium, χ2 = 0.125.
Values set in italics denote statistical significance.