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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Trends Biotechnol. 2016 Oct 26;35(4):308–317. doi: 10.1016/j.tibtech.2016.10.001

Figure 1. Workflow of a Paper-Based ZIKV Biosensor Based on CRISPR Technology.

Figure 1

A) Proposed workflow for a CRISPR (clustered regularly interspaced short palindromic repeats) - associated protein-9 nuclease (CRISPR-Cas9) based engineered paper sensor to detect the ZIKV RNA genome, B) illustration of zika/dengue virus sensing according to work flow. Figure adapted with permission from [32].