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. Author manuscript; available in PMC: 2017 Mar 27.
Published in final edited form as: Oncogene. 2016 Sep 26;36(13):1770–1778. doi: 10.1038/onc.2016.353

Figure 4.

Figure 4

GT-CAF exosomes increase cell number and survival of epithelial cells. (a) L3.6 cells were treated with GFP-CD63-CAF1 conditioned media for 48 hours and exosome uptake was visualized. (b) L3.6 cells were treated with L3.6, GT-PANC1, or GT-CAF1 exosomes for 6 days and total cells were counted. (c) L3.6 cells were treated with L3.6, GT-PANC1 or GT-CAF1 exosomes for 6 days and 1µM GEM for 3 days, and live cells were counted. (d) PANC1 cells were treated with PANC1 or GT-CAF1 exosomes for 6 days. AsPC1 cells were treated with AsPC1 or GT-CAF1 exosomes for 6 days. Total cells were counted. (e) PANC1 cells were treated with PANC1 or GT-CAF1 exosomes for 6 days, and AsPC1 cells were treated with AsPC1 or GT-CAF1 exosomes for 6 days. All cells were then treated with 1µM GEM for 3 days, and live cells were counted. *p-value<0.05; **p-value<0.01