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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Photochem Photobiol. 2016 Nov 1;93(4):1008–1015. doi: 10.1111/php.12642

Table 2.

UVB radiation suppresses generation of Th1 (IFNγ) and Th2 (IL-10) cytokine production by cultured splenocytes stimulated in vitro by mitogen (Anti-CD3e MoAb) 90 min after radiation.#

Treatment of mice IFNγ concentration

IFNγ IL-10
pg/mL
Sham (control) 2,470 ± 362 70 ± 11
UVB (400 mJ/cm2) 300 ± 94** 30 ± 12*
#

Splenocytes from UVB- or Sham-treated mice (90 min later) were stimulated for 48 h with anti-CD3e MoAb and harvested supernatants were analyzed for levels of IFNγ and IL-10 as described in the Materials and Methods section. Data presented as mean ± SEM (n=6–7),

**

P<0.01, or

*

P<0.05 by Student’s t-test.