Table 2.

Results of serum laboratory investigations for the pediatric and adult groups.

Test	Children			Adults			p
	Results	Abnormal results (%)	Reference range	Results	Abnormal results (%)	Reference range
WBC	7.1 (4.7, 11.1)	0	4–14	4.4 (4.1, 8.1)	13	4–11	0.038
Hemoglobin	145 (133, 165)	7	110–157	171 (171, 177)	25	137–180	0.0001
Platelets	232 (129, 323)	14	150–400	120 (109, 183)	75	150–400	0.0004
INR	1.3 (1.1, 1.6)	86	0.9–1.1	1.2 (1.1, 1.6)	50	0.9–1.1	0.38
PTT	34 (31, 40)	43	25–35	34 (33, 38)	25	25–35	0.36
CRP	0 (0, 2.6)	0	0–8	2.2 (1.2, 8.8)	13	0–8	0.0004
AFP	1.2 (0.5, 3.6)	0	0–10	2.3 (1.9, 3.5)	0	0–10	0.0044
Albumin	41 (37, 44)	0	33–48	43 (43, 47)	0	33–48	0.074
Total protein	66 (63, 75)	0	63–80	76 (69, 83)	25	63–80	0.015
ALP	225 (120, 382)	0	45–450	97 (35, 147)	38	30–130	0.0002
ALT	19 (13, 30)	0	1–35	28 (16, 44)	13	1–60	0.16
AST	30 (24, 37)	0	10–45	27 (22, 34)	13	8–40	0.19
α-2-Macroglobulin	3.2 (2, 3.6)	71	1.02–2.59	2.5 (2.8, 3.3)	38	1.02–2.59	0.15
Bilirubin (total)	8 (4, 21)	21	0–14	14 (14, 27)	43	0–24	0.027
Bilirubin (direct)	3 (1, 6)	0	0–7	5.5 (4, 8)	50*	0–7	0.032
GGT	42 (24, 89)	29	11–63	67 (43, 332)	63	11–63	0.05
Haptoglobin	0.3 (0.06, 1.2)	50	0.3–2	0.4 (0.3, 0.9)	38	0.3–2	0.75
Apolipoprotein-A1	1.17 (0.9, 1.6)	29	1.04–2.02	1.28 (1.24, 1.42)	0	1.04–2.02	0.18
Factor VII	0.54 (0.29, 0.74)	36	≥0.50	0.49 (0.62, 0.68)	67	≥0.50	0.77
FibroTest	0.45 (0.22, 0.69)	93	<0.21	0.61 (0.49, 0.75)	100	<0.21	0.13

Results are shown as median (10th, 90th percentiles). Those tests that were significantly different between groups (p < 0.05) are highlighted in bold. For the pediatric group, N = 11–14 and for the adult group, N = 5–8.

WBC, white blood cell; INR, international normalized ratio; PTT, partial thromboplastin time; CRP, C-reactive protein; AFP, α-fetoprotein; ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate transaminase; GGT, gamma-glutamyl transpeptidase.

*The number of abnormalities was significantly different between groups (p < 0.05).