FIGURE 3.

Bias in natural circular code codon contents in detected delRNA_3-1 as compared to the rest of the human mitogenome, as a function of the contribution of that codon to RFR. Natural circular code codon identities are indicated near datapoints, together with numbers of codons within delRNAs, followed by that number in the rest of the del-transformed human mitogenome. The Pearson correlation coefficient r = –0.602 (one-tailed P = 0.0025) and the nonparametric Spearman rank correlation coefficient rs = –0.637 (one tailed P = 0.001) indicate that circular code codons with high effects on frame maintenance are avoided.