Table 3.
Genotype distributions of ERAP1, IL23R and PTGER4 SNPs and HLA-B27 status of mild and severe radiographic AS patients*.
| Mild radiographic AS (n = 171) | Severe radiographic AS (n = 64) | P value | |
|---|---|---|---|
| HLA-B27 positivity | 95 (55.6%) | 47 (73.4) | 0.013 |
| ERAP1 rs27044 | 0.69 | ||
| CC | 85 (49.7) | 29 (45.3) | |
| CG | 77 (45) | 30 (46.9) | |
| GG | 9 (5.3) | 5 (7.8) | |
| ERAP1 rs30187 | 0.66 | ||
| CC | 59 (34.5) | 19 (29.7) | |
| TC | 87 (50.9) | 33 (51.6) | |
| TT | 25 (15.6) | 12 (18.8) | |
| IL23R rs11209032 | 0.43 | ||
| GG | 54 (31.6) | 18 (28.1) | |
| AG | 80 (46.8) | 27 (42.2) | |
| AA | 37 (21.6) | 19 (29.7) | |
| PTGER4 rs10440635 | 0.62 | ||
| GG | 47 (27.5) | 17 (26.6) | |
| AG | 83 (48.5) | 35 (54.7) | |
| AA | 41 (24) | 12 (18.8) | |
*Values are provided as n (%).