Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 13;2017:8048720. doi: 10.1155/2017/8048720

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Yong-Jik Lee et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Schematic illustration for hypothetical reaction mechanisms of fimasartan in nonalcoholic fatty liver disease. Amelioration of nonalcoholic fatty liver disease by fimasartan is mainly accomplished with catabolic activation such as the sequential regulation of PPARδ→ AMPK → PGC-1α. In addition, Aster glehni lowers triglyceride accumulation in liver by inhibiting 11β-HSDH1, ACC, FAS, and TNF-α; also, its effect is additionally exerted by activating adiponectin, MCD, and MCAD. Meaning of symbols: arrow means activation, up and horizontal line means inhibition, and X means blocking.