Figure 3. ABLs promote intracellular mycobacterial killing by a ROS dependent mechanism.

dTHP1 cells were infected with BCG at the MOI of 5 and then treated for 3 days with ABLs carrying PA, PI3P, or PI5P in the presence or absence of 100 U/ml PEG-Cat. Results are expressed as mean ± standard deviation of CFU values performed in triplicate and are representative of two independent experiments. *p < 0.01 and **p < 0.0001 by one sided Student’s t test.