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. 2017 Mar 27;7:45305. doi: 10.1038/srep45305

Figure 3. Reelin promotes myeloma cell glycolysis.

Figure 3

(A–C) Reelin knockdown suppresses H929 cell glycolysis. H929 cells with Reelin-specific siRNAs or control siRNA for 40 hours. The levels of LDH (A), L-Lactate (B) and glucose uptake (C) were then measured. (D,E) Reelin over-expression alters the response of H929 cells to glycolysis inhibitors. H929 cells were transfected with pCrl or vector for 40 hours. The cells were then seeded in FN-coated plates with different concentrations of oxamate (0–100 mmol/L) (D) or 2-deoxy-D-glucose (2-DG) (0–5 mmol/L) (E). The cells were analyzed by CCK8 method 24 hours later.