Figure 3. Multivariate Cox regression analysis for independent prognostic factors and nomogram for predicting 3- and 5-year overall survival in patients with gastric cancer.

(a) Multivariate Cox regression analysis identified the independent prognostic factors for overall survival of patients with gastric cancer. (b) Nomogram for predicting clinical outcomes integrated LOX-1 expression (Low/High) with tumor size (<5 cm/ > = 5 cm) and distant metastasis (Absent/Present). In the nomogram, higher total point predicts worse prognosis. Addition of tumor size, distant metastasis and LOX-1 expression for each patient correspondingly gives the total point. (c) Calibration plot for nomogram predicted and observed 3-year survival rate. (d) Calibration plot for nomogram predicted and observed 5-year survival rate. Line of dashes: ideal model; vertical bars, 95% confident interval.