Table 2. Univariate analyses for overall survival in 100 patients with gastric cancer.
| Factors | Overall survival |
|
|---|---|---|
| HR (95% CI) | P value | |
| Age (y) | ||
| <65 | Reference | 0.053 |
| > = 65 | 1.601 (0.993–2.580) | |
| Gender | ||
| Female | Reference | 0.484 |
| Male | 0.838 (0.508–1.379) | |
| Tumor size (cm) | ||
| <5 | Reference | 0.019 |
| > = 5 | 1.774 (1.099–2.864) | |
| Tumor location | ||
| Proximal + middle | Reference | 0.070 |
| Distal + unspecific | 0.624 (0.348–1.119) | |
| Borrmann classification | ||
| I + II | Reference | 0.010 |
| III + IV | 1.903 (1.170–3.096) | |
| Differentiation | ||
| Moderately | Reference | 0.079 |
| Poorly | 1.577 (0.949–2.621) | |
| Tumor invasion depth | ||
| T1 + T2 | Reference | 0.026 |
| T3 + T4 | 1.988 (1.086–3.674) | |
| Lymph node metastasis | ||
| Absent (N0) | Reference | 0.036 |
| Present (N1 + N2 + N3) | 1.700 (1.035–2.793) | |
| Distant metastasis | ||
| Absent (M0) | Reference | <0.001 |
| Present (M1) | 22.42 (5.881–85.43) | |
| LOX-1 expression | ||
| Low | Reference | <0.001 |
| High | 3.386 (2.068–5.544) | |
HR, Hazard ratio; CI, Confidence interval; P < 0.05 was considered to be statistically significant.