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. 2017 Mar 27;7:45273. doi: 10.1038/srep45273

Figure 8.

Figure 8

Exploratory connectivity analysis of salience networks, seeded from (A,B) bilateral anterior insula; and (C,D) bilateral posterior insula. (A) The anterior insula show increased functional connectivity with the ACC (p(FWE clus.) = 0.021, k = 84, p(FWE peak) = 0.995, Z = 3.88, [2, 46, 4]) in the naturalistic compared to artificial condition. (B) Main effect of soundscape on extracted connectivity scores between the anterior insula and ACC, with increased functional connectivity in the naturalistic condition compared to the artificial (t(16) = 2.71, p = 0.016) and no-soundscape control condition (t(16) = 3.09, p = 0.007). (C) The posterior insula show increased functional connectivity with a region of the right STS (p(FWE clus.) = 0.002, k = 121, p(FWE peak) = 0.511, Z = 4.54, [60, −24, 4]) in the artificial condition compared to the naturalistic condition. (D) Main effect of soundscape on extracted connectivity scores between the posterior insula and the right STS, with increased functional connectivity in the artificial condition compared to the naturalistic (t(16) = 5.01, p < 0.001) and no-soundscape control condition (t(16) = 2.85, p = 0.012). Error bars ± 1 SEM. *p < 0.05 **p < 0.01 ***p < 0.001.