Table 3. Distribution of autosomal CNVs in the parental genomes of RPL cases compared to controls with no history of recurrent pregnancy loss.
CNVs | RPL cases n = 25 | CNVs per genome | Controls n = 24 | CNVs per genome |
---|---|---|---|---|
All | 220 | 8.80 | 218 | 9.08 |
>300 kb | 19 | 0.76 | 9 | 0.38 |
Pericentromeric | 8 | 0.32 | 3 | 0.13 |
Subtelomeric | 4 | 0.16 | 0 | 0 |
Control group consists of couples, who had normal term pregnancies (n = 8) and women who had undergone elective termination of uncomplicated 1st trimester pregnancy (n = 8).