Table 4. Genes whose expression is modulated by 3 nM ouabain and 30 nM MBG after 96-h incubation.
| Gene symbol | Affymetrix ID | 3 nM ouabain, fold of modulation/p-value | 30 nM MBG, fold of modulation/p-value |
|---|---|---|---|
| FOS | 7975779 | 33.28/8.84E-07 | 13.29/4.84E-06 |
| ZFP36 | 8028652 | 20.36/9.39E-07 | 6.09/7.00E-06 |
| EGR1 | 8108370 | 15.33/3.86E-05 | 21.43/6.11E-08 |
| ADAMTS1 | 8069676 | 13.04/8.84E-07 | 5.01/4.04E-04 |
| PTGS2 | 7922976 | 11.36/1.38E-06 | 9.02/4.46E-06 |
| EGR2 | 7933872 | 8.09/9.39E-07 | 10.19/6.06E-07 |
| ATF3 | 7909610 | 7.39/6.40E-06 | 8.13/5.14E-06 |
| ARRDC4 | 7986350 | 5.62/2.45E-06 | NC |
| NR4A1 | 7955589 | 5.39/2.13E-05 | 7.29/3.30E-06 |
| NR4A3 | 8156848 | 5.38/2.09E-05 | 6.00/5.25E-05 |
| STC1 | 8149825 | 5.35/4.84E-04 | NC |
| JUNB | 8026047 | 5.06/3.43E-06 | 1.53/5.87E-03 |
| KLF4 | 8163002 | 4.70/3.66E-05 | 3.03/1.21E-04 |
| DUSP1 | 8115831 | 4.52/3.32E-06 | 6.09/3.33E-05 |
| ADAMTS5 | 8069689 | 4.43/2.58E-05 | 2.16/2.01E-03 |
| NR4A2 | 8055952 | 4.15/1.28E-04 | 2.99/4.56E-04 |
| SNAI1 | 8063382 | 3.87/8.20E-06 | NC |
| HEY1 | 8151457 | 3.75/1.21E-05 | 1.84/9.12E-03 |
| SOCS3 | 8018864 | 3.75/7.12E-06 | NC |
| VTRNA1–3 | 8108631 | 3.64/5.49E-05 | 2.76/3.12E-04 |
| JUN | 7916609 | 3.17/6.40E-06 | 4.72/3.60E-05 |
| KITLG | 7965322 | 3.05/3.99E-05 | 1.44/8.66E-03 |
| C7orf53 | 8135532 | 3.00/6.76E-04 | 1.33/8.66E-03 |
| EGR3 | 8149720 | 2.98/1.48E-04 | 3.07/3.09E-04 |
| GDF15 | 8027002 | 2.98/9.39E-07 | NC |
| IDI2 | 7931748 | 2.87/1.55E-03 | NC |
| BAMBI | 7926875 | 2.80/4.30E-04 | 1.29/1.68E-02 |
| EFNB2 | 7972713 | 2.79/1.44E-05 | 1.52/6.33E-03 |
| GEM | 8151816 | 2.77/6.90E-04 | 2.71/7.67E-04 |
| ABCG2 | 8101675 | 2.76/2.27E-06 | NC |
| SNORD3A | 8005547 | 2.72/2.03E-05 | NC |
| FAM71A | 7909624 | 2.66/1.36E-04 | 1.70/4.02E-04 |
| IER2 | 8026163 | 2.65/8.00E-05 | 1.54/9.03E-03 |
| HIST2H2BE | 7919637 | 2.60/1.13E-04 | 1.67/7.66E-04 |
| INSIG1 | 8137526 | 2.58/1.44E-05 | 1.25/9.33E-03 |
| PROX1 | 7909681 | 2.52/2.45E-06 | 2.70/5.01E-04 |
| HEY2 | 8121850 | 2.52/1.32E-04 | 2.07/9.81E-04 |
| CA8 | 8150978 | 2.50/1.28E-03 | NC |
| HIST1H1T | 8124402 | 2.48/7.76E-03 | 1.32/8.08E-03 |
| TNFSF9 | 8025053 | 2.47/1.45E-04 | 3.71/9.91E-05 |
| DLL4 | 7982854 | 2.46/1.30E-05 | NC |
| PTHLH | 7962000 | 2.39/8.00E-05 | NC |
| APOLD1 | 7954055 | 2.36/4.48E-04 | NC |
| GUCY1B3 | 8097973 | 2.34/1.01E-05 | NC |
| IGFBP5 | 8058857 | 2.28/8.16E-03 | 1.60/4.00E-03 |
| SPRY4 | 8114797 | 2.28/2.56E-03 | 1.79/2.83E-03 |
| BCL6 | 8092691 | 2.27/2.27E-06 | NC |
| HIST2H4A | 7905067 | 2.24/1.01E-04 | 1.88/4.31E-03 |
| KCNJ2 | 8009502 | 2.24/8.00E-05 | 2.00/7.01E-04 |
| TSC22D2 | 8083324 | 2.24/6.58E-05 | NC |
| DDIT3 | 7964460 | 2.23/1.06E-03 | 2.78/3.33E-04 |
| C2orf61 | 8052004 | 2.23/1.61E-03 | NC |
| HIST1H2BG | 8124423 | 2.19/7.34E-03 | NC |
| HES1 | 8084880 | 2.19/2.45E-06 | 2.21/4.41E-04 |
| ELMOD1 | 7943562 | 2.18/1.25E-04 | NC |
| MAFB | 8066266 | 2.16/9.95E-04 | 1.89/2.08E-03 |
| HIST1H2BD | 8117382 | 2.13/2.18E-03 | NC |
| SNORD75 | 7922416 | 2.11/6.89E-04 | −1.39/8.88E-03 |
| ADAMTS9 | 8088560 | 2.10/1.30E-05 | 2.09/7.51E-04 |
| ADAMTS4 | 7921821 | 2.09/2.67E-04 | 1.97/8.31E-04 |
| KLF5 | 7969414 | 2.07/6.49E-04 | 1.62/1.51E-03 |
| HIST2H2AA3 | 7905079 | 2.05/1.30E-04 | NC |
| NEFM | 8145361 | 2.04/6.82E-03 | −1.25/6.77E-03 |
| PCDH17 | 7969330 | 2.04/1.13E-04 | NC |
| TXNIP | 7904726 | 2.03/1.30E-05 | 2.22/6.89E-04 |
| FJX1 | 7939365 | 2.03/2.41E-02 | −1.33/9.38E-03 |
| BHLHE40 | 8077441 | 2.03/1.80E-05 | NC |
| ID2 | 8040103 | 2.02/2.60E-03 | 1.73/2.21E-05 |
| G0S2 | 7909441 | 2.02/3.87E-04 | 2.06/7.66E-05 |
| IDI1 | 7931754 | 2.01/1.39E-04 | 1.21/4.61E-03 |
| MIRLET7C | 8067944 | −2,03/3.36E-03 | NC |
| DTL | 7909568 | −2.05/8.00E-05 | NC |
| KIAA1370 | 7988970 | −2.07/4.94E-06 | 1.22/2.99E-03 |
| FAM111B | 7940147 | −2.18/2.72E-03 | −1.59/2.27E-03 |
| PDK4 | 8141094 | −2.32/4.18E-05 | −1.48/8.72E-04 |
| TRA2A | 8138592 | −2.40/3.39E-04 | NC |
| EIF5 | 7977058 | −2.52/6.54E-05 | −2.59/4.72E-05 |
| FBXO32 | 8152703 | −2.71/1.95E-04 | −1.73/3.70E-04 |
The table lists transcripts whose expression was changed in ouabain-treated cells by more than 2.0-fold.