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. Author manuscript; available in PMC: 2017 Jul 15.
Published in final edited form as: Neuroimage. 2016 Apr 30;135:311–323. doi: 10.1016/j.neuroimage.2016.04.041

Fig. 1.

Fig. 1

Outline of the proposed method for inter-site dMRI data harmonization and the section numbers where we discuss the related sub-problems. In our pipeline, the reference and the target sites are shown in green and red, respectively. Given the input images represented by their corresponding SH coefficients, we start by extracting a set of RISH features followed by updating the Freesurfer label map and finding a proper region-wise mapping for the RISH features as well as a voxel-wise mapping for the SH coefficients. The mapped coefficients are then used to estimate the harmonized dMRI signal of the target site making it statistically similar to the reference site.