Table 1.
WT Codon |
gene |
Mutation* |
Sequence 5′>3′ |
CAG | P53 | Q192X | CUG GCC CCU CCU UAG CAU CUU AUC |
CGA | P53 | R213X | AGA AAC ACU UUU UGA CAU AGU GUG |
CAG | P53 | E298X | GAG CCU CAC CAC UAG CUG CCC CCA |
UUA | APC | L360X | CUC AUC CAG CUU UGA CAU GGC AAU |
CGA | APC | R1114X | UCA GAA ACA AAU UGA GUG GGU UCU |
CAA | APC | Q1131X | CAG UCU UUG UGU UAA GAA GAU GAC |
Mutations are named by the position and the nature of the wild-type amino acid in p53 protein sequence.