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. 2017 Jan 12;15(3):1179–1187. doi: 10.3892/mmr.2017.6111

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Relative expression of (A) MRP1, GST, BCL-2 LRP, and (B) Topo-II at the mRNA level in pumc-91/ADM cells determined using reverse transcription-quantitative polymerase chain reaction. Cells were treated with different concentrations of RES (0, 10, 50 and 100 µM) for 48 h. The group not treated with RES (0 µM) was considered to be the control group. Data are expressed as a ratio of target gene to GAPDH, the housekeeping gene used. *P<0.05 vs. control group. MRP1, multi-drug resistance 1; GST, glutathione S-transferase; BCL-2, B cell leukemia/lymphoma 2; LRP, lung resistance protein; Topo-II, topoisomerase II; RES, reservatrol.