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. 2017 Feb 14;37(4):1989–1997. doi: 10.3892/or.2017.5443

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — XWLC05 ERCC1-shRNA cell line and its control xenograft tumor burden in mice with or without the treatment of cisplatin. (A and B) In vivo tumorigenesis examined by animal assay and subcutaneous tumor growth from mice injected with XWLC05 ERCC1-shRNA cell line and its control with or without the treatment of cisplatin (n=7 for each group, P<0.05 in XWLC05 ERCC1-shRNA groups). Error bars 95% CIs. Images show tumor volume and tumor weight of mice at the end of observation. (C) Immunohistochemical staining of xenograft tumor tissues. Tissues were stained with rabbit anti-ERCC1 antibody and visualized with goat anti-rabbit secondary antibody (magnification of ×400).