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. 2017 Feb 28;37(4):1971–1979. doi: 10.3892/or.2017.5479

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Copyright: © Shan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — CAF glycolytic metabolism. (A and B) Glucose uptake and lactate production in cancer-associated fibroblasts (CAFs) were significantly increased compared to that in normal fibroblasts (NFs). (C and D) PCR and western blot results showed that LDHA and PKM2 mRNA and protien were highly expressed in CAFs. (E and F) Results of statistical analysis. The results relative to control cells are presented as a standard ratio; *P<0.05 by t-test.