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. 2017 Feb 28;37(4):1971–1979. doi: 10.3892/or.2017.5479

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Copyright: © Shan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Effect of cancer-associated fibroblasts (CAFs) on pancreatic cancer MMP-2 and MMP-9 mRNA and protein levels. (A and C) The PCR results showed that MMP-2 and MMP-9 mRNA levels were significantly higher in the CAF-CM group than in the control group. (B and D) Western blot results showed that the levels of MMP-2 and MMP-9 protein expression were significantly increased compared to that in the control group; *P<0.05. CAF-CM, cancer-associated fibroblast-cultured medium; NF-CM, normal fibroblast-cultured medium.