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. 2017 Feb 28;37(4):1971–1979. doi: 10.3892/or.2017.5479

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Copyright: © Shan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — Impact of removing ‘CAF-cancer cell’ metabolic coupling upon pancreatic cancer progression. (A) The results showed that after removal of ‘cancer cell-CAF’ metabolic coupling, there was no significant difference in cell invasion ability among the three groups. (B and D) The PCR results showed there was no significant difference in MMP-2 and MMP-9 mRNA levels among the three groups. (C and E) The western blot results showed there was no significant difference in MMP-2 and MMP-9 protein levels among the three groups. CAF, cancer-associated fibroblast.