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. 2017 Jan 23;15(3):1037–1042. doi: 10.3892/mmr.2017.6135

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Copyright: © Ye et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — miR-141 expression levels in CSCs and CRC tumor tissue. (A) Differentially expressed miRNAs in CD133⁺ (a marker of CSCs) and CD133⁻ cells. Red denotes high and green denotes low levels of expression in CD133⁺ cells compared with CD133⁻ cells. (B) miR-141 expression levels in CD133⁺ and CD133⁻ Y cells were verified using RT-qPCR. *P<0.05 vs. CD133⁻. (C) miR-141 expression levels in fresh CRC tissues and adjacent healthy tissues from eight patients, as assessed by RT-qPCR. The y-axis indicates the fold change. *P<0.05 vs. paired sample. miR, microRNA; CSCs, cancer stem cells; CRC, colorectal cancer; CD, cluster of differentiation; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.