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Cyclin D2 is a novel target of miR-141 in CRC. (A) The predicted binding site of miR-141 in the cyclin D2 3′ untranslated region. (B) CRC cells were transfected with a negative control mimic, an miR-141 mimic or an anti-miR-141 inhibitor. The protein expression levels of cyclin D2 were detected by western blotting. GAPDH served as a loading control. CRC, colorectal cancer; miR, microRNA; NC, negative control.
