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. Author manuscript; available in PMC: 2017 Mar 27.
Published in final edited form as: Adv Virus Res. 2016 Sep 1;97:107–141. doi: 10.1016/bs.aivir.2016.07.002

Fig. 6.

Fig. 6

Detailed comparison of hexameric and interhexameric interfaces in HSV-1 A/B, C/D, and HCMV crystal lattices, and the PRV lattice model. (A) Interfaces are colored hotpink (hexameric), dark blue (dimeric), and teal (trimeric) to match the representative hexamer, dimer, and trimer in Fig. 5A. Bar diagrams (B) are colored according to the same color scheme. Hexameric interfaces are very similar in both HSV-1 and the HCMV lattices. In PRV, this interface is shifted toward the center of the molecule in this orientation. These differences are also apparent in the bar diagram. HSV-1 C/D and HCMV lattices also have overlapping dimeric and trimeric interfaces, whereas in the HSV-1 A/B lattice, the trimeric and dimeric interactions are almost completely reversed. Interfaces in the PRV lattice differ from those in the other three lattices.