Figure 6.

(top) Kinetic trapping in BD simulations. The magnitude of trapping P_int measured in BD simulations is shown in the limit of very high subunit binding strength (ε_b = 40). Results are shown as a function of the high affinity trapping parameter $p_{\text{trap}}=f_{\mathrm{A}}^m{N}^2$, with m = 1 or 2 respectively for the ‘No Induced Fit’ and ‘Induced Fit’ cases (see Eq. (10)) and N = 20. The parameter f_A was tuned by varying g_A/k_BT from 1 to 6. Other parameters are as in Fig. 3. (bottom) Relationship between capsid size and sensitivity to trapping in the high-affinity limit from the master equation. The magnitude of trapping P_int calculated for g_b = −25 is shown for the three conformation cases and capsid sizes N ∈ [20, 240]. The parameter f_A was tuned by varying g_A/k_BT from 0 to 10.