Fig. 1.

Principal component analysis comparing Oxford Biobank participants with 11 different human populations from the HapMap project. (A) Data is shown for British Caucasian individuals from Oxfordshire participating in OBB (5553 people) and for individuals from 11 HapMap populations (1397 people) using genome-wide SNP typing. First and second principal components shown plotted as eigenvectors (EV). ASW (African ancestry in Southwest USA, n = 87); CEU (Utah residents with Northern and Western European ancestry from the CEPH collection, 165); CHB (Han Chinese in Beijing China, 137); CHD (Chinese in Metropolitan Denver Colorado, 109); GIH (Gujarati Indians in Houston Texas, 101); JPT (Japanese in Tokyo Japan 113); LWK (Luhya in Webuye Kenya 110), MEX (Mexican ancestry in Los Angeles, California 86); MKK (Maasai in Kinyawa Kenya 184); TSI (Toscani in Italia, 102); YRI (Yoruba in Ibadan Nigeria, 203). (B) PCA restricted to SNPs in the MHC region.