Table 1.
Demographic and clinical characteristics of study participants.a
| Characteristic | Categories | Psilocybin first |
Niacin first |
Total |
|||
|---|---|---|---|---|---|---|---|
| n=14 | n=15 | n=29 | |||||
| Sex | Female | 7 | 50% | 11 | 73% | 18 | 62% |
| Male | 7 | 50% | 4 | 27% | 11 | 38% | |
| Age; mean (SD) | Range 22–75 | 52 (15.03) | 60.27 (9.45) | 56.28 (12.93) | |||
| Race | White/Caucasian | 13 | 93% | 13 | 87% | 26 | 90% |
| Black/African American | 0 | 0% | 0 | 0% | 0 | 0% | |
| Hispanic/Latino | 0 | 0% | 0 | 0% | 0 | 0% | |
| Asian | 0 | 0% | 0 | 0% | 0 | 0% | |
| American Indian/Native American | 0 | 0% | 0 | 0% | 0 | 0% | |
| Other | 1 | 7% | 2 | 13% | 3 | 10% | |
| Religious/spiritual beliefs | Atheist/agnostic | 4 | 29% | 10 | 67% | 14 | 48% |
| Jewish | 4 | 29% | 1 | 7% | 5 | 17% | |
| Catholic | 2 | 14% | 0 | 0% | 2 | 7% | |
| Other Christian | 3 | 21% | 1 | 7% | 4 | 14% | |
| Other faith/tradition | 1 | 7% | 3 | 20% | 4 | 14% | |
| Site of cancer | Breast | 4 | 29% | 5 | 33% | 9 | 31% |
| Reproductive | 3 | 21% | 5 | 33% | 8 | 28% | |
| Digestive cancers | 3 | 21% | 2 | 13% | 5 | 17% | |
| Lymphoma/leukemia | 2 | 14% | 2 | 13% | 4 | 14% | |
| Other types | 2 | 14% | 1 | 7% | 3 | 10% | |
| Stage of cancer | Stage IV | 3 | 21% | 7 | 47% | 10 | 34% |
| Stage III | 4 | 29% | 4 | 27% | 8 | 28% | |
| Stage II | 1 | 7% | 4 | 27% | 5 | 17% | |
| Stage I | 5 | 36% | 0 | 0% | 5 | 17% | |
| Other | 1 | 7% | 0 | 0% | 1 | 3% | |
| SCID (DSM-IV) diagnosisb | Adjustment disorder w/anxiety and depressed mood, chronic | 2 | 14% | 6 | 40% | 8 | 28% |
| Adjustment disorder w/anxiety, chronic | 10 | 71% | 8 | 53% | 18 | 62% | |
| Generalized anxiety disorder | 2 | 14% | 1 | 7% | 3 | 10% | |
| Hallucinogen use | No | 7 | 50% | 6 | 40% | 13 | 45% |
| Yes | 7 | 50% | 9 | 60% | 16 | 55% | |
| Employment status | Full-time employed | 6 | 43% | 5 | 33% | 12 | 41% |
| Part-time employed | 2 | 14% | 2 | 13% | 4 | 14% | |
| Full-time student | 1 | 7% | 0 | 0% | 1 | 3% | |
| Unemployed | 2 | 14% | 1 | 7% | 2 | 7% | |
| Self-employed | 1 | 7% | 1 | 7% | 2 | 7% | |
| Retired | 0 | 0% | 6 | 40% | 6 | 21% | |
| Long-term disability | 2 | 14% | 0 | 0% | 2 | 7% | |
| Educational attainment | Grade 7–12 w/o graduating high school | 1 | 7% | 0 | 0% | 1 | 3% |
| Graduated HS or equivalent | 0 | 0% | 1 | 7% | 1 | 3% | |
| Part college | 1 | 7% | 3 | 20% | 4 | 14% | |
| Graduated 4-year college | 5 | 36% | 4 | 27% | 9 | 31% | |
| Completed grad/professional school | 7 | 50% | 7 | 47% | 14 | 48% | |
| Marital status | Never married | 5 | 36% | 3 | 20% | 8 | 28% |
| Widowed | 0 | 0% | 2 | 13% | 2 | 7% | |
| Cohabitation | 2 | 14% | 0 | 0% | 2 | 7% | |
| Divorced | 1 | 7% | 3 | 20% | 4 | 14% | |
| Married | 6 | 43% | 7 | 47% | 13 | 45% | |
| Living arrangements | Live with spouse/partner/family | 11 | 79% | 9 | 60% | 20 | 69% |
| Live alone | 2 | 14% | 6 | 40% | 8 | 28% | |
| Other; lived with roommates | 1 | 7% | 0 | 0% | 1 | 3% | |
a
The two dose-sequence groups did not significantly differ on any demographic or clinical characteristic measures.
b
Psychiatric classification was based on the structured clinical interview for the DSM-IV (SCID-IV).
Nearly two-thirds (59%) of participants had previously been treated with anti-depressant or anxiolytic medication, but none were on any psychotropics before study enrollment per inclusion/exclusion criteria.