Table 3.
Participant ratings on questionnaires completed 7 hours after psilocybin administration+.
| Questionnaire and subscale description | Low dose (post-session) |
High dose (post-session) |
|---|---|---|
| Hallucinogen Rating Scale (HRS) | ||
| Intensity | 36.47 (2.78) | 63.76 (2.34)*** |
| Somesthesia | 15.38 (1.55) | 35.62 (2.75)*** |
| Affect | 23.79 (2.13) | 44.60 (2.54)*** |
| Perception | 12.92 (1.76) | 41.18 (2.78)*** |
| Cognition | 18.88 (2.09) | 43.08 (2.54)*** |
| Volition | 30.81 (2.02) | 37.06 (1.88)* |
| 5 Dimension Altered States of Consciousness (5D-ASC) | ||
| Oceanic boundlessness (OBN) | 26.86 (3.73) | 63.99 (3.78)*** |
| Dread of ego dissolution (DED) | 6.89 (1.50) | 19.21 (2.38)*** |
| Visionary restructuralization (VRS) | 22.41 (2.99) | 61.16 (3.48)*** |
| Auditory alterations (AUA) | 6.72 (1.87) | 14.88 (2.18)*** |
| Vigilance reduction (VIR) | 22.74 (2.70) | 30.85 (2.24)** |
| Mystical Experience Questionnaire (MEQ30) | ||
| Mystical | 24.34 (3.83) | 59.58 (4.22)*** |
| Transcendence of time and space | 22.38 (2.90) | 62.08 (3.38)*** |
| Positive mood | 35.84 (4.00) | 69.82 (3.82)*** |
| Ineffability | 30.80 (4.49) | 74.46 (3.67)*** |
| Total | 26.90 (3.44) | 63.64 (3.56)*** |
| Mysticism Scale (M scale) | ||
| Interpretation | 48.95 (3.54) | 71.45 (2.24)*** |
| Introvertive | 44.53 (3.21) | 71.20 (2.14)*** |
| Extrovertive | 37.48 (3.19) | 64.58 (2.81)*** |
| Total | 49.36 (3.51) | 77.38 (2.40)*** |
+
All data are expressed as a percentage of maximum possible score. Data are means (1 SEM) for questionnaires completed 7 h after the low-dose (n = 50) and high-dose (n = 50) sessions collapsed across the two dose sequence groups. Asterisks indicate significant differences from the low dose (*p<0.05, **p<0.01, ***p<0.001).