Table 3.
Cutoff of nasal FENO for diagnosis of AR classified by population
| Nasal FENO | Cutoff, (ppb) | Sensitivity (%) | 95% CI | Specificity (%) | 95% CI | +LR | 95% CI | −LR | 95% CI |
|---|---|---|---|---|---|---|---|---|---|
| AR | |||||||||
| Children | 775 | 92.68 | 80.1–98.5 | 91.67 | 61.5–99.8 | 11.12 | 1.7–72.8 | 0.080 | 0.03–0.2 |
| Adults | 799 | 92.63 | 85.4–97.0 | 95.00 | 75.1–99.9 | 18.53 | 2.7–125.3 | 0.078 | 0.04–0.2 |
| GP | 799 | 92.65 | 86.9–96.4 | 96.87 | 83.8–99.9 | 29.65 | 4.3–204.2 | 0.076 | 0.04–0.1 |
| AR–asthma | |||||||||
| Children | 1458 | 72.97 | 61.4–82.6 | 95.83 | 78.9–99.9 | 17.51 | 2.6–119.9 | 0.28 | 0.2–0.4 |
| Adults | 990 | 98.47 | 94.6–99.8 | 92.86 | 66.1–99.8 | 13.79 | 2.1–91.1 | 0.016 | 0.004–0.07 |
| GP | 1271 | 82.44 | 76.5–87.4 | 94.74 | 82.3–99.4 | 15.66 | 4.1–60.4 | 0.19 | 0.1–0.3 |
Abbreviations: AR, allergic rhinitis; CI, confidence interval; FENO, fractional exhaled nitric oxide; GP, general population; LR, likelihood ratios; ppb, parts per billion.