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. 2017 Mar 23;12:2243–2254. doi: 10.2147/IJN.S130842

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© 2017 Xu et al. This work is published and licensed by Dove Medical Press Limited

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The relative cellular viability of rat neuronal cells cultured with different concentrations of PEG-b-(PELG-g-PLL) and TNF-α/PEG-b-(PELG-g-PLL) (n=5).

Notes: Data are expressed as mean ± SD. The block copolymer exhibited low cytotoxicity against neuronal cells and high relative cell viability (minimum mean waŝ85.5%), even when administered at a maximum dose of 1.0 μg/mL. *P<0.05, **P<0.01 vs relative cell viability at a concentration of 0 μg/mL.

Abbreviations: TNF-α, tumor necrosis factor-α; P, polymer; PEG-b-(PELG-g-PLL), poly(ethylene glycol)-b-(poly(ethylenediamine L-glutamate)-g-poly(L-lysine)); SD, standard deviation.