Table 2.
Allele and genotype distribution of the SMOC2 (G>A) polymorphism in male and female primary glaucoma patients
| Genotype/allele | Male (n=103) N (Frequency %) |
Female (n=101) N (Frequency %) |
P-value | RR | EFa/PF | Odds ratio (95% CI) |
|---|---|---|---|---|---|---|
| GG | 41 (39.80) | 36 (35.64) | 0.56 | 0.83 | 0.77 | Reference |
| GA | 56 (54.36) | 61 (60.39) | 0.39 | 1.2 | 0.11a | 1.24 (0.69–2.20) |
| AA | 06 (5.82) | 04 (3.92) | 0.75 | 0.66 | 0.05 | 0.75 (0.19–2.90) |
| G | 138 (67) | 133 (65.84) | 0.83 | 0.94 | 0.02 | 1.05 (0.69–1.58) |
| A | 68 (33) | 69 (34.16) | 0.83 | 1.05 | 0.02a |
Note:
a
Data for EF.
Abbreviations: N, number of subjects; RR, relative risk; EF, etiological fraction; PF, preventive fraction.