Table 4.
Comparison of allele and genotype distribution of the SMOC2 (G>A) polymorphism between POAG patients and controls
| Genotype/allele | Controls (n=202) N (Frequency %) |
POAG (n=140) N (Frequency %) |
P-value | RR | EFa/PF | Odds ratio (95% CI) |
|---|---|---|---|---|---|---|
| GG | 95 (47.29) | 65 (46.42) | 0.99 | 0.97 | 0.01 | Reference |
| GA | 90 (44.55) | 70 (50) | 0.34 | 1.24 | 0.08a | 1.13 (0.72–1.77) |
| AA | 17 (8.41) | 05 (3.5) | 0.07 | 0.40 | 0.25 | 0.43 (0.15–1.22) |
| G | 280 (69.30) | 200 (71.42) | 0.67 | 1.10 | 0.10a | 0.90 (0.64–1.26) |
| A | 124 (30.69) | 80 (28.57) | 0.67 | 0.90 | 0.03 |
Note:
a
Data for EF.
Abbreviations: POAG, primary open angle glaucoma; N, number of subjects; RR, relative risk; EF, etiological fraction; PF, preventive fraction.