Skip to main content
. Author manuscript; available in PMC: 2018 Mar 25.
Published in final edited form as: Biochem Biophys Res Commun. 2017 Feb 10;485(1):195–200. doi: 10.1016/j.bbrc.2017.02.051

Figure 4. Leflunomide fails to induce pulmonary and hepatic NQO1 enzyme in neonatal AhR-null mice.

Figure 4

The lung and liver tissues of neonatal AhR-null mice treated as mentioned in Figure 3 were harvested to determine pulmonary and hepatic NQO1 mRNA (A and C) and protein (B and D) expression. Additionally, the lung and liver tissues of neonatal WT mice treated with 3-methylcholanthrene (MC) (n=3) as mentioned in Figure 3 were harvested for analysis of NQO1 induction. MC-treated mice were used as positive controls. Significant differences between PEG- and MC-treated animals are indicated by *, p < 0.05.