Table 3.
Associations between protease activity and eGFR.
| Protease | Beta | SE | p | FDR | n |
|---|---|---|---|---|---|
| ACE2 | −0.135 | 0.040 | 8.00E-04 | 0.008 | 268 |
| DPP4 | −0.744 | 0.252 | 0.003 | 0.017 | 268 |
| ACE | −0.846 | 0.378 | 0.026 | 0.065 | 268 |
| PREP | −0.231 | 0.102 | 0.024 | 0.065 | 268 |
| ENPEP | −0.148 | 0.083 | 0.075 | 0.150 | 268 |
| LNPEP | −0.164 | 0.170 | 0.334 | 0.477 | 268 |
| NPEPPS | 0.173 | 0.179 | 0.334 | 0.477 | 268 |
| LAP3 | 0.365 | 0.485 | 0.452 | 0.503 | 268 |
| RNPEP | 0.350 | 0.460 | 0.447 | 0.503 | 268 |
| ANPEP | 0.504 | 0.770 | 0.513 | 0.513 | 268 |
ACE. angiotensin I-converting enzyme; ACE2: angiotensin I-converting enzyme 2; ANPEP: memnrane alanyl-aminopeptidase (APN); DPP4: dipeptidyl peptidase 4; ENPEP: glutamyl-aminopeptidase (APA); LAP3: leucine aminopeptidase 3; LNPEP: leucyl/cystinyl aminopeptidase; NPEPPS: aminopeptidase puromycine sensitive (PSA); PREP: prolyl endopeptidase (PEP); RNPEP: arginyl aminopeptidase (APB); eGFR: estimated glomerular filtration rate; FDR: false discovery rate (statistically significant values are shown in bold); SE: standard error.
Results from linear regression models adjusted for age in years and sex. Results were adjusted for multiple testing by applying the FDR.