Table 1. Clinical characteristics of 256 patients with nontuberculous mycobacterial infections and Mycobacterium tuberculosis infections.
Clinical findinga | NTM (%) (n = 128) | TB (%) (n = 128) | P-value | |
---|---|---|---|---|
Age (years, mean±SD)b | 60.8±13.1 | 60.2±10.4 | 0.666 | |
Gender | >0.999 | |||
Male | 79 (61.7) | 79 (61.7) | ||
Female | 49 (38.3) | 49 (38.3) | ||
BMIb | 20.3±3.0 | 22.1±2.9 | <0.001 | |
Smoking | <0.001 | |||
Current smoker | 14 (10.9) | 49 (38.3) | ||
Ex-smoker | 44 (34.4) | 39 (30.5) | ||
Never smoker | 70 (54.7) | 40 (31.3) | ||
Previous PTB history | 62 (48.4) | 17 (13.3) | <0.001 | |
Underlying disease | ||||
DM | 14 (10.9) | 46 (35.9) | <0.001 | |
Status of diabetes control | 0.535* | |||
• Well-controlled DM | 7 (50) | 63) | ||
• Uncontrolled DM | 7 (50) | 17 (37) | ||
Malignancy | 9 (7.0) | 17 (13.3) | 0.098 | |
Chronic lung disease | ||||
COPD | 12 (9.4) | 23 (18) | <0.045 | |
ILD | 11 (8.6) | 5 (3.9) | 0.121 | |
Symptom | ||||
Cough | 107 (83.6) | 82(64.1) | <0.001 | |
Sputum | 91 (71.1) | 69(53.9) | 0.005 | |
Hemoptysis | 35 (27.3) | 16(12.5) | 0.003 | |
Dyspnea | 1 (0.8) | 19(14.8) | <0.001 | |
Fever | 9 (7.0) | 5(3.9) | 0.272 | |
Laboratory findingb | ||||
Albumin (g/dL, mean±SD) | 3.7±0.6 | 3.5±0.6 | 0.091 | |
White blood cell (uL, mean±SD) | 6880±2068 | 7365±2209 | 0.074 | |
C-reactive protein (mg/dL, mean±SD) | 1.6±2.0 | 2.4±3.3 | 0.051 |
NTM = Nontuberculous mycobacteria, TB = Mycobacterium tuberculosis infection, SD = standard deviation, BMI = body mass index, COPD = chronic obstructive pulmonary disease, ILD = interstitial lung disease.
*Significance within DM patients, not in the whole study population
a chi-square test
b Student’s t-test