. 2017 Mar 20;11:901–908. doi: 10.2147/DDDT.S131316

Table 1.

Changes in level of creatinine, urea, and uric acid in the serum after treatment with CDDP, NAC, and TAU both individually and in combination

Groups	Creatinine, mg/dL	Urea, mg/dL	Uric acid, mg/dL
Control	0.84^a±0.06	34.13^a±3.39	0.37^a±0.05
NAC	0.78^a±0.08	30.33^a±2.29	0.38^a±0.06
TAU	0.91^a±0.08	36.41^a±2.08	0.54^a,b±0.07
NAC–TAU	0.80^a±0.05	33.50^a±2.09	0.41^a±0.06
CDDP	2.50^c±0.18	68.40^c±6.43	2.10^c±0.12
CDDP–NAC	1.23^b±0.07	40.86^a,d±3.25	0.96^b±0.04
CDDP–TAU	1.66^d±0.32	47.20^d±3.74	1.19^d±0.13
CDDP–NAC–TAU	1.02^a±0.21	36.80^a±2.80	0.43^a±0.06

Notes: Each value represents the mean ± standard error for each experimental group (n=6). Mean values within the same column not sharing a common superscript (a–d) are significantly different (P≤0.05).

Abbreviations: CDDP, cisplatin; NAC, N-acetylcysteine; TAU, taurine.