Table 2.
Bivariate associations of PAI-1 with lung function, metabolic, cardiac, and inflammatory markers in patients with COPD
| R | P-value | |
|---|---|---|
| Age, years | −0.22 | 0.058 |
| Body mass index, kg/m2 | 0.01 | 0.93 |
| Waist circumference, cm | −0.01 | 0.96 |
| FEV1 %predicted | −0.07 | 0.55 |
| Log-triglycerides, mg/dL | 0.31 | 0.007 |
| High-density lipoprotein cholesterol, mg/dL | −0.23 | 0.044 |
| Fasting plasma glucose, mg/dL | −0.16 | 0.19 |
| Ankle–brachial index | −0.02 | 0.36 |
| Log-NT-proBNP, pg/mL | 0.05 | 0.68 |
| Log-hs-CRP, mg/L | 0.25 | 0.035 |
| Log-adiponectin, ng/mL | −0.23 | 0.048 |
Notes: Bivariate associations were analyzed by using Pearson correlations. NT-proBNP, triglycerides, hs-CRP, and adiponectin were log-transformed to obtain a normal distribution.
Abbreviations: COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; hs-CRP, high-sensitive C-reactive protein; NT-proBNP, N-terminal pro-B-type natriuretic peptide; PAI-1, plasminogen activator inhibitor-1.