Table 2. Global and regional distribution volume ratios (DVRs).
DVR | Whole sample | Lower tertile* | Middle tertile | Upper tertile* |
---|---|---|---|---|
N | N=55 | N=18 | N=19 | N=18 |
Mean cortical DVR | 1.17(0.26) | 0.93(0.02) | 1.08(0.09) | 1.49(0.16) |
Orbitofrontal gyrus | 1.09(0.27) | 0.86(0.04) | 0.1(0.14) | 1.40(0.19) |
Prefrontal gyrus | 1.11(0.29) | 0.86(0.04) | 1.02(0.13) | 1.46(0.19) |
Superior frontal gyrus | 1.20(0.34) | 0.90(0.04) | 1.08(0.14) | 1.61(0.22) |
Parietal lobe | 1.14(0.24) | 0.92(0.05) | 1.07(0.08) | 1.42(0.19) |
Medial temporal gyrus | 1.01(0.09) | 0.95(0.07) | 1.01(0.06) | 1.06(0.11) |
Lateral temporal gyrus | 1.13(0.24) | 0.93(0.03) | 1.05(0.12) | 1.41(0.19) |
Occipital gyrus | 1.08(0.13) | 0.99(0.06) | 1.06(0.07) | 1.19(0.15) |
Anterior cingulate gyrus | 1.27(0.34) | 0.97(0.07) | 1.17(0.18) | 1.67(0.23) |
Posterior cingulate gyrus | 1.32(0.35) | 1.02(0.06) | 1.19(0.1) | 1.76(0.23) |
Data are presented as mean (SD) distribution volume ratio.
All DVR measures are significantly higher in the upper tertile than the lower tertile (p<0.005). Data in bold indicate greater than DVR positivity cut-off of 1.062 for cDVR, indicating more than minimal Aβ.