Figure 2.

Artonin E induces morphological features of apoptosis in MCF-7 cells.

Notes: (A) Untreated breast cancer cells, (B) MCF-7 cells treated for 24 h with 3 µM, (C) 10 µM, (D) 30 µM, and (E) quantification of viable, apoptotic, and necrotic cells at both 24 and 48 h. *Means differ significantly from that of control at P<0.05. All values are expressed as mean ± standard deviation of three independent experiments.

Abbreviations: BL, cell membrane blebbing; EA, early apoptosis; VC, viable cells; CC, cancer control; LA, late apoptosis; MN, marginated nuclear chromatin; SN, secondary necrosis.