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. 2017 Mar 20;11:865–879. doi: 10.2147/DDDT.S124324

Table 2.

Relative mRNA level of expression of apoptosis and cell cycle-related genes in MCF-7 cells after treatment with 10 µM Artonin E for 24 h

No Gene Relative expression (% Log [fold change])
1 Bcl-2 −13.8±0.09
2 Cyc 19.0a±0.01
3 Bax 15.5a±0.04
4 MAPK 8 −21.1b±0.06
5 Apaf1 6.4±0.04
6 Akt1 −6.8±0.05
7 Caspase 7 51.8a±0.03
8 Caspase 8 8.8±0.01
9 Caspase 9 17.3a±0.02
10 Cyclin D −23.7b±0.19
11 Cyclin E −15.3±0.09
12 p21 23.7a±0.05

Notes: Values are expressed as mean ± standard deviation of three replicates at P<0.05.

a

Significantly upregulated,

b

Significantly downregulated.